MOTS-C 10mg

MOTS-c is a mitochondrial-derived peptide, a short peptide whose sequence is encoded within the mitochondrial 12S ribosomal RNA region of mitochondrial DNA rather than the nuclear genome. Sova supplies it as a lyophilised research powder, CAS number 1627580-64-6, with a molecular weight of 2174.50. It is catalogued within the Longevity research category and provided as a laboratory reagent for controlled study.

As one of the mitochondrial-derived peptides, MOTS-c is studied for its role in metabolic regulation and the cellular stress response. Research describes it translocating to the nucleus under metabolic stress, where it is associated with pathways involving AMP-activated protein kinase and adaptive gene expression. These mechanisms place it within investigations of how mitochondria communicate with the rest of the cell.

MOTS-c is of particular interest in longevity and exercise-metabolism research, where investigators examine its links to insulin sensitivity, glucose utilisation and metabolic homeostasis in model systems. Studies also consider how its levels respond to exercise and metabolic demand. This work is confined to preclinical and laboratory research settings, and Sova supplies the peptide solely to support such investigations.

Each batch of MOTS-c UK stock from Sova is verified by reverse-phase HPLC and ESI mass spectrometry, with the data recorded on a batch-linked Certificate of Analysis. The lyophilised powder should be stored sealed, protected from light and kept frozen for long-term stability. Sova is a UK-based supplier dispatching domestically. This material is supplied strictly for laboratory research use only and not for human or veterinary use.