GH secretagogues · GHRH analogue · mod GRF 1-29
CJC-1295 No-DAC 5mg
CJC-1295 No-DAC supplied as a lyophilised powder for reconstitution. Reference-grade purity, mass-spec confirmed identity, and a batch-linked Certificate of Analysis with every order.
CJC-1295 No-DAC UK buying guide →
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About the compound
What is CJC-1295 No-DAC?
CJC-1295 No-DAC, also known as modified GRF 1-29, is a synthetic analogue of growth-hormone-releasing hormone based on its first twenty-nine amino acids. It carries CAS number 863288-34-0 and a molecular weight of 3367.85. The No-DAC designation indicates it lacks the drug-affinity complex present in the DAC version, giving it a short half-life and a comparatively brief, pulse-like activity profile in research models.
Mechanistically, CJC-1295 No-DAC is examined as a GHRH-receptor agonist that, in experimental models, is reported to prompt growth-hormone release from the pituitary. Because it lacks the drug-affinity complex, studies describe a short-acting profile that produces a pulsatile rather than sustained signal. This kinetic behaviour is a key reason the compound is distinguished from the longer-acting DAC variant throughout the research literature and study design.
Within growth-hormone research, CJC-1295 No-DAC is studied for its GHRH-analogue activity and its short, pulsatile secretion profile in laboratory and animal models. It is frequently paired with ipamorelin, a ghrelin-receptor agonist, in studies exploring complementary secretagogue pathways. Laboratories sourcing CJC-1295 No-DAC UK stock generally reference these published designs when characterising GHRH-analogue behaviour under controlled experimental conditions.
Sova Peptides supplies CJC-1295 No-DAC as a lyophilised research material for in-vitro and laboratory study by qualified researchers. Each batch is characterised by reverse-phase HPLC and ESI mass spectrometry, with a batch-linked Certificate of Analysis provided to confirm identity and molecular weight. Standard lyophilised-peptide storage and handling apply. This product is supplied strictly for laboratory research use only and is not for human or veterinary use.
Specification
Read the vial.
- Compound
- CJC-1295 No-DAC
- CAS number
- 863288-34-0
- Molecular weight
- 3367.85 g/mol
- Purity (HPLC)
- 99.0%
- Identity
- Confirmed by mass spectrometry
- Form
- Lyophilised powder, sterile-filtered
- Storage
- Store lyophilised at ≤ −20 °C, protected from light. Reconstituted: 2–8 °C, use within 28 days.
- Batch
- SVA-0391
Reconstitution guidance
Handled like a lab reagent.
Reconstitute with bacteriostatic water. Draw slowly against the vial wall — do not agitate. Swirl gently until fully dissolved. Store reconstituted vials at 2–8 °C and use within 28 days. Full protocol on the Certificate of Analysis.
Example dilutions · 5 mg vial
| BAC water | Concentration | Per 0.05 ml |
|---|---|---|
| 1.0 ml | 5 mg / ml | 0.25 mg |
| 2.0 ml | 2.50 mg / ml | 0.13 mg |
| 3.0 ml | 1.67 mg / ml | 0.08 mg |
| 5.0 ml | 1 mg / ml | 0.05 mg |
Concentration reference only — not a dosing schedule.
FAQ
CJC-1295 No-DAC, answered.
What is CJC-1295 No-DAC?
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CJC-1295 No-DAC, or modified GRF 1-29, is a synthetic GHRH analogue based on the first twenty-nine amino acids of growth-hormone-releasing hormone. It has CAS number 863288-34-0 and a molecular weight of 3367.85, and lacks the drug-affinity complex, giving it a short half-life in research models.
Is CJC-1295 No-DAC legal to buy in the UK?
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CJC-1295 No-DAC is not a licensed medicine in the UK and is supplied strictly as a research chemical for laboratory use only. Purchase and supply for that purpose are permitted when it is not marketed for human consumption, with compliant handling the responsibility of the purchasing researcher.
What is CJC-1295 No-DAC studied for?
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CJC-1295 No-DAC is investigated in the research literature for its GHRH-analogue activity and its short, pulsatile influence on growth-hormone release in cell and animal models. This work is exploratory and confined to laboratory settings, and does not establish any effect in humans.
How is Sova's CJC-1295 No-DAC verified?
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Each batch of Sova's CJC-1295 No-DAC is analysed by reverse-phase HPLC for identity and by ESI mass spectrometry to confirm its molecular weight against the expected 3367.85. A batch-linked Certificate of Analysis accompanies every lot so researchers can trace the exact material.
How should CJC-1295 No-DAC be stored?
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Lyophilised CJC-1295 No-DAC is generally kept cold and shielded from light, refrigerated briefly and frozen for longer-term storage. After reconstitution for research, solutions are typically refrigerated and used within a limited timeframe, with containers sealed against moisture and repeated freeze-thaw cycling.
How does No-DAC differ from the DAC version?
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The key distinction is the drug-affinity complex: the No-DAC version lacks it, producing a short half-life and pulsatile profile, whereas the DAC version binds albumin for a much longer duration of action. Researchers select between them depending on whether a brief or sustained secretion profile suits their model.
Further reading
Research hub →6 min read
CJC-1295 vs Ipamorelin: A Research Guide
A mechanism-focused comparison of CJC-1295 and Ipamorelin, two synthetic growth-hormone secretagogues that engage distinct receptors within the somatotropic axis.
6 min read
How Research Peptides Are Verified
How reputable suppliers confirm the identity and purity of a research peptide using reverse-phase HPLC and mass spectrometry, and what a batch-linked Certificate of Analysis should tell a researcher.
6 min read
Understanding a Certificate of Analysis
A practical, research-use guide to what a Certificate of Analysis contains, what each field means, and how to tell a genuine batch-linked CoA from a meaningless one.