5-Amino-1MQ 50mg

5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide within the NAD+ salvage pathway. It is not a peptide but a low-molecular-weight compound (CAS 42464-96-0, molecular weight 159.21). Sova supplies 5-Amino-1MQ UK as a single 50mg vial intended for controlled laboratory work, giving research groups a defined quantity of the parent compound for reconstitution and characterisation.

By occupying the active site of NNMT, the compound is used as a tool for probing how NNMT activity influences intracellular nicotinamide levels and NAD+ turnover. Because NNMT is expressed at high levels in adipose tissue, much of the surrounding literature examines adipocyte energy handling and metabolic flux. In these settings 5-Amino-1MQ serves to interrogate enzyme kinetics rather than to produce any physiological outcome.

Published research has positioned NNMT inhibition within metabolic and adipocyte-energy studies, where the enzyme sits at the intersection of methylation capacity and the NAD+ salvage pathway. The compound therefore appears in in-vitro and preclinical models exploring cellular bioenergetics. Sova provides it purely as a characterised reference material, allowing laboratories to design their own assays around a known, batch-documented starting point without any implied use in humans.

As a small molecule, 5-Amino-1MQ is verified by HPLC to confirm identity and purity rather than by peptide mass-spectrometry sequencing, with results recorded on a batch-linked Certificate of Analysis supplied alongside the vial. Store the sealed vial cool, dry and protected from light. Sova is a UK-based supplier providing this material for laboratory research use only, and it is not for human or animal consumption.